Bowel

As with other arteries such as those supplying the kidneys, clots can occur in the blood vessels supplying the bowel.

APS patients whose intestinal blood supply is affected by a clot can experience sudden and severe abdominal pain, fever, vomiting, diarrhoea and blood in the stool. In some cases major surgery will be required to remove part of the bowel.

If the intestinal arteries become partially blocked or narrowed by clots, this can lead to a condition known as abdominal angina (known medically as mesenteric angina). The main symptom is stomach pain usually experienced after eating a big meal – a time when the bowel needs its best blood supply.

Treatment with anticoagulants has been shown to be effective in a number of patients, but others have to have part of the bowel removed. The patient who kindly agreed to be the case study in the 2015 British Medical Journal’s A Patient’s Journey had a large clot in her bowel.

Diagnosis and treatment

APS is usually diagnosed from a combination of a positive blood test and symptoms. If you are under 50 and have suffered a thrombosis, or have had more than one pregnancy loss, you should discuss with your doctor whether you need blood tests.

Related conditions

Some people with APS will also have other autoimmune conditions, as may their family members. APS has been linked with many other autoimmune conditions, including rheumatoid arthritis, lupus, Raynaud’s phenomenon, and Sjögren’s syndrome.

Newly diagnosed

Receiving a new diagnosis of APS can be frightening, and no doubt you will want to know exactly what APS is. Following this, you will likely have a great many more questions to ask about the condition and how it can affect you. We are here to help!

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Our mission is to achieve earlier diagnosis and offer support to anyone affected by antiphospholipid syndrome (APS) through awareness, education and research.

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